Current Trials

Current Trials (actively recruiting):

TEMPO-2 (Calgary Stroke Program): A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion

https://clinicaltrials.gov/ct2/show/NCT02398656

ESCAPE NA-1 (NoNo Inc): A Randomized Controlled Trial of NA-1 for Acute Stroke selected for Endovascular Revascularization

https://clinicaltrials.gov/ct2/show/NCT02930018

PROPHECY (Boehringer-Ingleheim Canada): Prospective Validation of Predictive Features of Paroxysmal Atrial Fibrillation

FRONTIER (NoNo Inc): Field Randomization of NA-1 Therapy in Early Responders

https://clinicaltrials.gov/ct2/show/NCT02315443

CREST-2 (NIH-NINDS): Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

https://clinicaltrials.gov/ct2/show/NCT02089217

NASPAF ICH (PHRI): A Randomized Controlled Trial of NOACs for Atrial Fibrillation and previous ICH

https://clinicaltrials.gov/ct2/show/NCT02998905

TEC4Home (VCHRI/UBC & VGH Hospital Foundation): Home Telemonitoring Technology in Managing Hypertension among Stroke/TIA Patients

YOUNG ESUS (PCHRI/Bayer AG): Observational Study of Young Patients with Embolic Stroke of Undetermined Source (ESUS)

https://clinicaltrials.gov/ct2/show/NCT03185520

Stroke Permission to Contact REGISTRY (Heart and Stroke Foundation): Prospective Recruitment of Stroke Patients at Vancouver General Hospital and the Vancouver Stroke Program

COGNITION IN YOUNG STROKE (Heart and Stroke Foundation): Cognitive Deficits in Young Stroke Patients as Measured by the NIH Toolbox Cognitive Battery, MoCA and Spontaneous Speech

HI-ROLLER (UBC Dept of Neurology):high-Risk Patient Protocol for Left Atrial Appendage Closure

EMPOWER (CIHR): Engaging Persons With Cerebral Venous Thrombosis For Meaningful Outcomes And Peer Support

Follow-up only:

REDUCE (GORE Inc): A Randomized Controlled Trial of PFO closure plus antiplatelet versus standard of care for ESUS/TIA

Upcoming Trials:

SECRET (Canadian Stroke Consortium): Study of rivaroxaban for Cerebral Venous Thrombosis

CONVINCE (University College Dublin): Colchicine for Stroke Prevention in Non-cardio Embolic Stroke

https://clinicaltrials.gov/ct2/show/NCT02898610

RCVS-NIRS – Utility of Near-Infrared Spectroscopy and Transcranial Doppler Ultrasound in Suspected Reversible Cerebral Vasoconstriction Syndrome

Recently completed:

DATAS-II (CIHR): Dabigatran following Transient ischemic attack and minor Stroke

https://clinicaltrials.gov/ct2/show/NCT02295826

NAVIGATE-ESUS (Bayer): Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS)

https://clinicaltrials.gov/ct2/show/NCT02313909

POINT (NINDS-NETT/UCSF): Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial

https://clinicaltrials.gov/ct2/show/NCT00991029