Current Trials (actively recruiting):
ANNEXA-I – Trial of andexanet in ICH patients receiving an oral FXa inhibitor https://clinicaltrials.gov/ct2/show/NCT03661528
CATIS-ICAD (Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease), https://clinicaltrials.gov/ct2/show/NCT04142125
CONVINCE (University College Dublin): Colchicine for Stroke Prevention in Non-cardio Embolic Stroke
https://clinicaltrials.gov/ct2/show/NCT02898610
CREST-2 (NIH-NINDS): Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
https://clinicaltrials.gov/ct2/show/NCT02089217
EMPOWER (CIHR): Engaging Persons With Cerebral Venous Thrombosis For Meaningful Outcomes And Peer Support
FRONTIER (NoNo Inc): Field Randomization of NA-1 Therapy in Early Responders
https://clinicaltrials.gov/ct2/show/NCT02315443
HI-ROLLER (UBC Dept of Neurology):high-Risk Patient Protocol for Left Atrial Appendage Closure
PROPHECY (Boehringer-Ingleheim Canada): Prospective Validation of Predictive Features of Paroxysmal Atrial Fibrillation
SEARCH Study (StrokE and vAscular Risk factors contributing to neuroCognitive decline in adult
congenital Heart disease): https://www.vancouverstrokeprogram.com/research/search-study/
SECRET (Canadian Stroke Consortium): Study of rivaroxaban for Cerebral Venous Thrombosis
Stroke Permission to Contact REGISTRY (Heart and Stroke Foundation): Prospective Recruitment of Stroke Patients at Vancouver General Hospital and the Vancouver Stroke Program
TEMPO-2 (Calgary Stroke Program): A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion
https://clinicaltrials.gov/ct2/show/NCT02398656
TRIC-VCI https://clinicaltrials.gov/ct2/show/NCT04109963
Follow-up only:
REDUCE (GORE Inc): A Randomized Controlled Trial of PFO closure plus antiplatelet versus standard of care for ESUS/TIA
YOUNG ESUS (PCHRI/Bayer AG): Observational Study of Young Patients with Embolic Stroke of Undetermined Source (ESUS)
https://clinicaltrials.gov/ct2/show/NCT03185520
Upcoming Trials:
ARCADIA – Atrial cardiopathy and antithrombotic drugs in prevention after cryptogenic stroke https://clinicaltrials.gov/ct2/show/NCT03192215
AXIOMATIC-SSP – a study on BMS-986177 for the prevention of a stroke in patients receiving aspirin and clopidogrel https://www.clinicaltrials.gov/ct2/show/NCT03766581
EASI-TOC – Endovascular acute stroke intervention – Tandem occlusion trial https://clinicaltrials.gov/ct2/show/NCT04261478
RCVS-NIRS – Utility of Near-Infrared Spectroscopy and Transcranial Doppler Ultrasound in Suspected Reversible Cerebral Vasoconstriction Syndrome
Recently completed:
COGNITION IN YOUNG STROKE (Heart and Stroke Foundation): Cognitive Deficits in Young Stroke Patients as Measured by the NIH Toolbox Cognitive Battery, MoCA and Spontaneous Speech
DATAS-II (CIHR): Dabigatran following Transient ischemic attack and minor Stroke
https://clinicaltrials.gov/ct2/show/NCT02295826
ESCAPE NA-1 (NoNo Inc): A Randomized Controlled Trial of NA-1 for Acute Stroke selected for Endovascular Revascularization
https://clinicaltrials.gov/ct2/show/NCT02930018
NAVIGATE-ESUS (Bayer): Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS)
https://clinicaltrials.gov/ct2/show/NCT02313909
NASPAF ICH (PHRI): A Randomized Controlled Trial of NOACs for Atrial Fibrillation and previous ICH
https://clinicaltrials.gov/ct2/show/NCT02998905
POINT (NINDS-NETT/UCSF): Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
https://clinicaltrials.gov/ct2/show/NCT00991029
TEC4Home (VCHRI/UBC & VGH Hospital Foundation): Home Telemonitoring Technology in Managing Hypertension among Stroke/TIA Patients